21–27 Sept 2026
EuXFEL Lighthouse
Europe/Berlin timezone

How do you coordinate Electron microscope hardware, enabling smarter experiments?

22 Sept 2026, 18:15
1h 45m
EuXFEL Lighthouse

EuXFEL Lighthouse

Poster Experiments automation Poster Session & Reception

Speaker

Utkarsh Pratiush (University of Tennessee, Knoxville)

Description

Note: Please see attachment, it has figure and references

Data-driven methods are rapidly transforming experimental science [1], not only through advances in artificial intelligence but also by enabling scriptable access to scientific instruments [2]. Providing users with programmable control over instrumentation opens new opportunities for statistical analysis, adaptive experimentation, and more efficient materials discovery [3, 4, 5]. However, modern electron microscopy systems remain constrained by fragmented, vendor-specific hardware interfaces [4,5], limiting programmability and flexibility despite their substantial capital cost (often up to $10 million) [6].

In this talk, I will present a modular, vendor-agnostic framework for coordinating heterogeneous electron microscope hardware, where individual subsystems such as stage, scan, and detectors are abstracted as independent device-level services and orchestrated through a unified PyTango-based[6] control layer. This approach enables instruments to be accessed programmatically through scripting interfaces, allowing users to construct flexible, data-driven experimental workflows beyond traditional GUI-based operation. Figure 1 shows the schematic of the interface architecture and its realization in our university on a ThermoFisher spectra 300 microscope. Eventually our plan is to connect our interface with the BlueSky framework[8].

Code availability: https://github.com/pycroscopy/asyncroscopy

Authors

Utkarsh Pratiush (University of Tennessee, Knoxville) Mr Austin Houston (University of Tennessee, Knoxville) Mr Dominick Pelaia Mr Levi Dunn Prof. Sergei Kalinin (University of Tennessee, Knoxville) Prof. Gerd Duscher (University of Tennessee, Knoxville)

Presentation materials

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